World Health:(1) Neonatal screeningAfter 3 days of feeding, blood is collected from the amino acid disorder ends of the feet and then collected on thick recycled filter pape...
Apr 01,2022 | Janet
(1) Neonatal screening
After 3 days of feeding, blood is collected from the amino acid disorder ends of the feet and then collected on thick recycled filter paper that is dried at the local hospital and mailed to the screening center.
The screening center uses the guthrie bacterial growth inhibition test for semi-quantitative determination.
The principle is to use l-phenylalanine to stimulate the growth of an already inhibited Bacillus subtilis. The accuracy of disease detection is high and the probability of false positive is low.
(2) Urine iron trichloride test
Screening of older infants and children. The test uses the reaction of a ferric chloride solution with phenylalanine in the urine.
If there is an immediate green reaction, the urine is positive for a high concentration of phenylalanine.
The dinitrophenylhydrazine test can also be used to detect phenylalanine in urine. The principle is similar to that of the ferric chloride test, and a yellow precipitate is positive.
(3) Analysis of plasma amino acids and analysis of urine organic acids
This test can detect not only this condition, but also other amino acid deficiency conditions and related metabolic diseases
(4) Urine pterin analysis
To determine abnormal pterin levels in the body by analyzing urinary levels of neopterin and biopterin using high pressure liquid chromatography (PHLC).
(5) Enzymatic diagnosis
Pah is present only in liver cells and requires liver biopsy to detect the enzyme activity, which is not suitable for clinical diagnosis but usually only for academic research.
The activity of the other 3 enzymes can also be determined by extracting red, white or skin fibroblasts from peripheral blood.
(6) DNA analysis
Prenatal diagnosis is performed directly by DNA analysis in pregnant women who have the disease gene but no symptoms.
Hepatic damage and non-alcoholic fatty liver disease have both been linked to higher levels of circulating BCAA [77]. These findings showed that consuming large amounts of protein or amino acids can lead to further serious metabolic problems and liver damage.
Overconsumption of sulfur amino acids raises the risk of death and cardiovascular disease. According to this preliminary research, eating too many foods high in sulfur amino acids, which are predominantly present in proteins like beef, chicken, and dairy, may raise a person's risk of cardiovascular disease and death.
According to recent research, some people may experience more severe depression if they consume significant amounts of the amino acid proline, however this is primarily dependant on the microbiome of the individual.
- Hey, dads!Are you looking for the best HDTV antennaso that you can watch free TVcoming over the air through antennas?Then ...
Stock investment refers to the whole process of dividend distribution and capital gain for investors based on the purchase o...
Digital signal processing is the processing signal digitally using computers. In digital signal processing, we take digitize...
Working adults have limited time and money Working parents with small children do not have time to breathe in childcare, hou...
This consumer update isbrought to you by the U.S.Food and DrugAdministration.Sun safety is importantfor everyone, of all age...
The IoT industry is experiencing breakthroughs as different types of modules, chipsets and connectivity solutions are create...
Hard drive performance has always been an underrated aspect of overall system performance. The hard drive was considered onl...
JND Water is your trusted water cooler and dispenser supplier. Our products have maintained high quality throughout years an...
water dispenser water dispenser price in China ceramic water dispenser